Minimum 75 games played in the past 24 years. This reflects on-field performance of teams with at least a 50% winning percentage against In-State opponents. It does not include forfeits mandated by the FHSAA:
| RANK | SCHOOL | W | - | L | PCT |
| 1 | St. Thomas Aquinas (Fort Lauderdale) | 288 | - | 29 | 0.909 |
| 2 | Lakeland | 266 | - | 36 | 0.881 |
| 3 | Armwood (Seffner) | 269 | - | 46 | 0.854 |
| 4 | Madison County (Madison) | 244 | - | 44 | 0.847 |
| 5 | Bolles (Jacksonville) | 259 | - | 50 | 0.838 |
| 6 | Miami Central | 235 | - | 47 | 0.833 |
| 7 | Naples | 240 | - | 49 | 0.830 |
| 8 | St. Augustine | 243 | - | 50 | 0.829 |
| 9 | Trinity Christian (Jacksonville) | 243 | - | 56 | 0.813 |
| 10 | Cocoa | 230 | - | 58 | 0.799 |
| 11 | Mainland (Daytona Beach) | 233 | - | 62 | 0.790 |
| 12 | Christopher Columbus (Miami) | 223 | - | 61 | 0.785 |
| 13 | Dwyer (Palm Beach Gardens) | 219 | - | 61 | 0.782 |
| 14 | Apopka | 234 | - | 68 | 0.775 |
| 15 | Chaminade (Hollywood) | 219 | - | 64 | 0.774 |
| 16 | Jesuit (Tampa) | 225 | - | 67 | 0.771 |
| 17 | American Heritage (Plantation) | 211 | - | 63 | 0.770 |
| 18 | Vero Beach | 203 | - | 62 | 0.766 |
| 19 | University School (Fort Lauderdale) | 130 | - | 41 | 0.760 |
| 20 | Washington (Miami) | 215 | - | 70 | 0.754 |
| 21 | Wakulla (Crawfordville) | 205 | - | 67 | 0.754 |
| 22 | Niceville | 189 | - | 63 | 0.750 |
| 23 | Miami Northwestern | 217 | - | 73 | 0.748 |
| 24 | Lincoln (Tallahassee) | 202 | - | 68 | 0.748 |
| 25 | Plant (Tampa) | 211 | - | 75 | 0.738 |
| 26 | Venice | 212 | - | 77 | 0.734 |
| 27 | South Sumter (Bushnell) | 209 | - | 76 | 0.733 |
| 28 | Glades Central (Belle Glade) | 204 | - | 75 | 0.731 |
| 29 | Osceola (Kissimmee) | 212 | - | 80 | 0.726 |
| 30 | Lake Gibson (Lakeland) | 204 | - | 77 | 0.726 |
| 31 | Manatee (Bradenton) | 203 | - | 77 | 0.725 |
| 31 | Fort Meade | 203 | - | 77 | 0.725 |
| 33 | Clearwater Central Catholic | 207 | - | 79 | 0.724 |
| 34 | First Baptist (Naples) | 112 | - | 43 | 0.723 |
| 35 | Atlantic (Delray Beach) | 195 | - | 77 | 0.717 |
| 36 | North Florida Christian (Tallahassee) | 184 | - | 75 | 0.710 |
| 37 | Palm Bay (Melbourne) | 194 | - | 80 | 0.708 |
| 38 | Hillsborough (Tampa) | 188 | - | 79 | 0.704 |
| 39 | Cardinal Gibbons (Fort Lauderdale) | 187 | - | 79 | 0.703 |
| 40 | Edgewater (Orlando) | 203 | - | 86 | 0.702 |
| 41 | Fort Myers | 186 | - | 81 | 0.697 |
| 42 | Blountstown | 194 | - | 85 | 0.695 |
| 43 | Fletcher (Neptune Beach) | 184 | - | 81 | 0.694 |
| 44 | Lake Wales | 187 | - | 83 | 0.693 |
| 45 | Largo | 186 | - | 83 | 0.691 |
| 46 | Lafayette (Mayo) | 180 | - | 82 | 0.687 |
| 47 | Victory Christian (Lakeland) | 149 | - | 68 | 0.687 |
| 48 | Raines (Jacksonville) | 186 | - | 85 | 0.686 |
| 49 | Columbia (Lake City) | 188 | - | 86 | 0.686 |
| 50 | Bishop Moore (Orlando) | 185 | - | 85 | 0.685 |
| 51 | First Academy (Orlando) | 178 | - | 82 | 0.685 |
| 52 | American Heritage (Delray Beach) | 184 | - | 85 | 0.684 |
| 53 | Dunnellon | 177 | - | 82 | 0.683 |
| 54 | Dr. Phillips (Orlando) | 192 | - | 89 | 0.683 |
| 55 | Orlando Christian Prep | 98 | - | 46 | 0.681 |
| 56 | Pahokee | 182 | - | 87 | 0.677 |
| 57 | King’s Academy (West Palm Beach) | 166 | - | 82 | 0.669 |
| 58 | Port St. Joe | 180 | - | 89 | 0.669 |
| 59 | Trinity Catholic (Ocala) | 169 | - | 84 | 0.668 |
| 60 | South Dade (Homestead) | 175 | - | 87 | 0.668 |
| 61 | Winter Park | 177 | - | 88 | 0.668 |
| 62 | Lakeland Christian | 129 | - | 65 | 0.665 |
| 63 | Charlotte (Punta Gorda) | 180 | - | 91 | 0.664 |
| 64 | Merritt Island | 178 | - | 90 | 0.664 |
| 65 | Berkeley Prep (Tampa) | 165 | - | 84 | 0.663 |
| 66 | North Marion (Citra) | 184 | - | 94 | 0.662 |
| 67 | Baker County (Glen St. Mary) | 176 | - | 90 | 0.662 |
| 68 | Calvary Christian (Fort Lauderdale) | 131 | - | 67 | 0.662 |
| 69 | Dade Christian (Miami) | 132 | - | 68 | 0.660 |
| 70 | Champagnat Catholic (Hialeah) DEFUNCT | 89 | - | 46 | 0.659 |
| 71 | Godby (Tallahassee) | 174 | - | 91 | 0.657 |
| 72 | Bartram Trail (St. Johns) | 186 | - | 98 | 0.655 |
| 73 | Florida High "FSU" (Tallahassee) | 182 | - | 96 | 0.655 |
| 74 | Deerfield Beach | 176 | - | 93 | 0.654 |
| 75 | Hardee (Wauchula) | 168 | - | 89 | 0.654 |
| 76 | Nature Coast Tech (Brooksville) | 138 | - | 74 | 0.651 |
| 77 | Miramar | 171 | - | 92 | 0.650 |
| 78 | South Fort Myers | 133 | - | 72 | 0.649 |
| 79 | Landmark Christian (Haines City) DEFUNCT | 70 | - | 38 | 0.648 |
| 80 | Jefferson (Tampa) | 180 | - | 98 | 0.647 |
| 81 | Countryside (Clearwater) | 167 | - | 91 | 0.647 |
| 81 | Dixie County (Cross City) | 167 | - | 91 | 0.647 |
| 83 | Community School (Naples) | 88 | - | 48 | 0.647 |
| 84 | Pine Forest (Pensacola) | 163 | - | 89 | 0.647 |
| 85 | Plantation | 166 | - | 91 | 0.646 |
| 86 | University Christian (Jacksonville) | 175 | - | 96 | 0.646 |
| 87 | Gulliver Prep (Pinecrest) | 160 | - | 88 | 0.645 |
| 88 | Glades Day (Belle Glade) | 176 | - | 98 | 0.642 |
| 89 | Palm Beach Gardens | 168 | - | 94 | 0.641 |
| 90 | Hawthorne | 167 | - | 94 | 0.640 |
| 91 | Oviedo | 165 | - | 93 | 0.640 |
| 92 | Zephyrhills | 164 | - | 93 | 0.638 |
| 93 | Rockledge | 166 | - | 95 | 0.636 |
| 93 | Belen Jesuit (Miami) | 166 | - | 95 | 0.636 |
| 95 | Dunbar (Fort Myers) | 162 | - | 93 | 0.635 |
| 96 | Lake Brantley (Altamonte Springs) | 167 | - | 96 | 0.635 |
| 97 | Windermere Prep | 80 | - | 46 | 0.635 |
| 98 | Zephyrhills Christian | 57 | - | 33 | 0.633 |
| 99 | Cypress Bay (Weston) | 138 | - | 80 | 0.633 |
| 100 | Pace | 162 | - | 94 | 0.633 |
| 101 | Fleming Island (Orange Park) | 143 | - | 84 | 0.630 |
| 102 | Baker | 165 | - | 97 | 0.630 |
| 103 | Land O’Lakes | 157 | - | 93 | 0.628 |
| 104 | Park Vista (Lake Worth) | 124 | - | 74 | 0.626 |
| 105 | Monsignor Pace (Miami) | 160 | - | 96 | 0.625 |
| 106 | Boone (Orlando) | 167 | - | 101 | 0.623 |
| 107 | East Lake (Tarpon Springs) | 167 | - | 102 | 0.621 |
| 108 | Seminole (Sanford) | 166 | - | 103 | 0.617 |
| 109 | Winter Haven | 162 | - | 101 | 0.616 |
| 110 | Navarre | 152 | - | 95 | 0.615 |
| 111 | Ely (Pompano Beach) | 162 | - | 102 | 0.614 |
| 112 | Lake Mary | 158 | - | 100 | 0.612 |
| 113 | Tampa Bay Tech | 167 | - | 107 | 0.609 |
| 113 | Immokalee | 167 | - | 107 | 0.609 |
| 115 | Jupiter Christian | 134 | - | 86 | 0.609 |
| 116 | First Coast (Jacksonville) | 151 | - | 98 | 0.606 |
| 117 | Miami Norland | 153 | - | 100 | 0.605 |
| 118 | Springstead (Spring Hill) | 147 | - | 97 | 0.602 |
| 119 | Benjamin (Palm Beach Gardens) | 150 | - | 99 | 0.602 |
| 120 | Union County (Lake Butler) | 162 | - | 107 | 0.602 |
| 121 | Mitchell (New Port Richey) | 147 | - | 98 | 0.600 |
| 122 | Vanguard (Ocala) | 159 | - | 107 | 0.598 |
| 123 | Palmetto | 156 | - | 106 | 0.595 |
| 124 | Dillard (Fort Lauderdale) | 153 | - | 104 | 0.595 |
| 125 | Miami Southridge | 151 | - | 103 | 0.594 |
| 126 | The Villages | 120 | - | 82 | 0.594 |
| 127 | Pensacola Catholic | 152 | - | 104 | 0.594 |
| 128 | Clay (Green Cove Springs) | 160 | - | 110 | 0.593 |
| 129 | Bradford (Starke) | 157 | - | 108 | 0.592 |
| 130 | Heritage (Palm Bay) | 93 | - | 64 | 0.592 |
| 131 | Lakewood (St. Petersburg) | 159 | - | 110 | 0.591 |
| 132 | Miami Carol City | 156 | - | 108 | 0.591 |
| 133 | Hollywood Christian DEFUNCT | 62 | - | 43 | 0.590 |
| 134 | Warner Christian (South Daytona) | 138 | - | 96 | 0.590 |
| 135 | Buchholz (Gainesville) | 156 | - | 109 | 0.589 |
| 136 | Durant (Plant City) | 150 | - | 105 | 0.588 |
| 137 | Miami Killian | 154 | - | 108 | 0.588 |
| 138 | Florida Air (Melbourne) DEFUNCT | 54 | - | 38 | 0.587 |
| 139 | Riverview (Sarasota) | 156 | - | 110 | 0.586 |
| 140 | Boca Raton | 146 | - | 103 | 0.586 |
| 141 | Cardinal Newman (West Palm Beach) | 147 | - | 104 | 0.586 |
| 142 | Braden River (Bradenton) | 107 | - | 76 | 0.585 |
| 143 | Melbourne Central Catholic | 142 | - | 101 | 0.584 |
| 144 | Admiral Farragut (St. Petersburg) DEFUNCT | 117 | - | 84 | 0.582 |
| 145 | Holy Trinity (Melbourne) | 135 | - | 97 | 0.582 |
| 146 | Bishop Kenny (Jacksonville) | 146 | - | 105 | 0.582 |
| 147 | Timber Creek (Orlando) | 143 | - | 103 | 0.581 |
| 148 | Seminole Ridge (Loxahatchee) | 111 | - | 80 | 0.581 |
| 149 | Clewiston | 151 | - | 109 | 0.581 |
| 150 | Miami Palmetto | 144 | - | 104 | 0.581 |
| 151 | Foundation Academy (Winter Garden) | 107 | - | 78 | 0.578 |
| 152 | Ponte Vedra | 100 | - | 73 | 0.578 |
| 153 | Cambridge (Tampa) | 124 | - | 91 | 0.577 |
| 154 | St. Stephen's (Bradenton) | 95 | - | 70 | 0.576 |
| 155 | Palm Beach Central (Wellington) | 126 | - | 93 | 0.575 |
| 156 | Escambia (Pensacola) | 138 | - | 103 | 0.573 |
| 157 | Coral Gables | 142 | - | 106 | 0.573 |
| 158 | Gaither (Tampa) | 152 | - | 115 | 0.569 |
| 159 | Vernon | 145 | - | 111 | 0.566 |
| 160 | Liberty County (Bristol) | 141 | - | 108 | 0.566 |
| 161 | Tampa Catholic | 152 | - | 117 | 0.565 |
| 162 | Riverside (Jacksonville) | 145 | - | 112 | 0.564 |
| 163 | Astronaut (Titusville) | 144 | - | 112 | 0.563 |
| 164 | Northview (Bratt) | 131 | - | 102 | 0.562 |
| 165 | Jones (Orlando) | 147 | - | 115 | 0.561 |
| 166 | Bishop Verot (Fort Myers) | 144 | - | 113 | 0.560 |
| 167 | Seffner Christian | 82 | - | 65 | 0.558 |
| 168 | Ed White (Jacksonville) | 142 | - | 113 | 0.557 |
| 169 | East Ridge (Clermont) | 128 | - | 102 | 0.557 |
| 170 | Sebring | 135 | - | 108 | 0.556 |
| 171 | Treasure Coast (Port St. Lucie) | 102 | - | 82 | 0.554 |
| 172 | Legacy Charter (Ocoee) | 63 | - | 51 | 0.553 |
| 173 | Sandalwood (Jacksonville) | 137 | - | 111 | 0.552 |
| 174 | Lake Highland Prep (Orlando) | 134 | - | 109 | 0.551 |
| 175 | Canterbury (Ft. Myers) | 50 | - | 41 | 0.549 |
| 176 | Barron Collier (Naples) | 135 | - | 111 | 0.549 |
| 177 | Suwannee (Live Oak) | 141 | - | 116 | 0.549 |
| 177 | Pasco (Dade City) | 141 | - | 116 | 0.549 |
| 179 | Melbourne | 139 | - | 115 | 0.547 |
| 180 | East Bay (Gibsonton) | 135 | - | 112 | 0.547 |
| 181 | Southeast (Bradenton) | 138 | - | 115 | 0.545 |
| 182 | Carrollwood Day (Tampa) | 85 | - | 71 | 0.545 |
| 183 | John Carroll (Fort Pierce) | 135 | - | 113 | 0.544 |
| 184 | Fort White | 137 | - | 115 | 0.544 |
| 185 | Cardinal Mooney (Sarasota) | 138 | - | 117 | 0.541 |
| 186 | Flagler Palm Coast (Bunnell) | 133 | - | 113 | 0.541 |
| 187 | Homestead | 133 | - | 114 | 0.538 |
| 188 | Wharton (Tampa) | 137 | - | 118 | 0.537 |
| 189 | Faith Christian (Orlando) | 51 | - | 44 | 0.537 |
| 190 | Chipley | 134 | - | 116 | 0.536 |
| 191 | Hilliard | 130 | - | 113 | 0.535 |
| 192 | Western (Davie) | 131 | - | 114 | 0.535 |
| 193 | Westminster Christian (Miami) | 126 | - | 110 | 0.534 |
| 194 | Frostproof | 134 | - | 117 | 0.534 |
| 195 | Episcopal (Jacksonville) | 128 | - | 112 | 0.533 |
| 195 | Canterbury (St. Petersburg) DEFUNCT | 56 | - | 49 | 0.533 |
| 197 | Ransom Everglades (Miami) | 114 | - | 100 | 0.533 |
| 198 | Gainesville | 139 | - | 122 | 0.533 |
| 199 | Yulee | 100 | - | 88 | 0.532 |
| 200 | North Miami Beach | 130 | - | 115 | 0.531 |
| 200 | New Smyrna Beach | 130 | - | 115 | 0.531 |
| 202 | Newsome (Lithia) | 116 | - | 103 | 0.530 |
| 203 | Mosley (Lynn Haven) | 125 | - | 111 | 0.530 |
| 204 | Kathleen (Lakeland) | 134 | - | 119 | 0.530 |
| 205 | Trenton | 136 | - | 121 | 0.529 |
| 206 | Evangelical Christian (Fort Myers) | 132 | - | 118 | 0.528 |
| 207 | Mandarin (Jacksonville) | 134 | - | 120 | 0.528 |
| 208 | Port Charlotte | 129 | - | 116 | 0.527 |
| 209 | DeLand | 131 | - | 118 | 0.526 |
| 210 | Oak Hall (Gainesville) | 91 | - | 82 | 0.526 |
| 211 | Lake Minneola | 75 | - | 68 | 0.524 |
| 212 | Pine Crest (Fort Lauderdale) | 120 | - | 109 | 0.524 |
| 213 | Crestview | 125 | - | 114 | 0.523 |
| 214 | Pensacola | 127 | - | 116 | 0.523 |
| 215 | Douglas (Parkland) | 122 | - | 112 | 0.521 |
| 216 | Calvary Christian (Clearwater) | 112 | - | 103 | 0.521 |
| 217 | Westminster Academy (Fort Lauderdale) | 121 | - | 112 | 0.519 |
| 218 | Walton (DeFuniak Springs) | 126 | - | 117 | 0.519 |
| 219 | Newberry | 130 | - | 121 | 0.518 |
| 220 | Key West | 118 | - | 110 | 0.518 |
| 220 | St. John Neumann (Naples) | 118 | - | 110 | 0.518 |
| 222 | West Florida (Pensacola) | 106 | - | 99 | 0.517 |
| 223 | Steinbrenner (Lutz) | 77 | - | 72 | 0.517 |
| 224 | West Nassau (Callahan) | 126 | - | 118 | 0.516 |
| 225 | Hialeah | 120 | - | 113 | 0.515 |
| 226 | University (Orange City) | 71 | - | 67 | 0.514 |
| 227 | Andrew Jackson (Jacksonville) | 129 | - | 122 | 0.514 |
| 228 | Milton | 125 | - | 119 | 0.512 |
| 229 | Robinson (Tampa) | 129 | - | 123 | 0.512 |
| 230 | Wekiva (Apopka) | 91 | - | 87 | 0.511 |
| 231 | St. Andrew's (Boca Raton) | 113 | - | 109 | 0.509 |
| 232 | Moore Haven | 115 | - | 111 | 0.509 |
| 233 | North Broward Prep (Coconut Creek) | 120 | - | 116 | 0.508 |
| 234 | Choctawhatchee (Fort Walton Beach) | 123 | - | 119 | 0.508 |
| 235 | Nease (Ponte Vedra Beach) | 131 | - | 127 | 0.508 |
| 236 | Lake Nona (Orlando) | 77 | - | 75 | 0.507 |
| 237 | Sebastian River (Sebastian) | 120 | - | 117 | 0.506 |
| 237 | Sneads | 120 | - | 117 | 0.506 |
| 237 | Indian Rocks Christian (Largo) | 120 | - | 117 | 0.506 |
| 240 | Fort Pierce Westwood | 121 | - | 118 | 0.506 |
| 241 | Out-of-Door (Sarasota) | 83 | - | 81 | 0.506 |
| 242 | Plant City | 126 | - | 123 | 0.506 |
| 242 | Boyd Anderson (Lauderdale Lakes) | 126 | - | 123 | 0.506 |
| 244 | North Fort Myers | 123 | - | 121 | 0.504 |
| 245 | Seabreeze (Daytona Beach) | 129 | - | 127 | 0.504 |
| 246 | Oakleaf (Orange Park) | 68 | - | 67 | 0.504 |
| 247 | Ridge Community (Davenport) | 98 | - | 97 | 0.503 |
| 248 | Aucilla Christian (Monticello) | 100 | - | 99 | 0.503 |
| 249 | Archbishop McCarthy (Southwest Ranches) | 117 | - | 116 | 0.502 |
| 250 | Keystone Heights | 120 | - | 120 | 0.500 |
| 250 | Seven Rivers Christian (Lecanto) | 72 | - | 72 | 0.500 |
